The Colt Anaconda is a six-shot stainless double-action .44 Magnum built for handgun hunting and deliberate range work, and it has an MSRP of $1,699. It runs an oversized version of the Python's leaf-spring action, which Colt redesigned for the Anaconda's return in 2021.

The barrel sits under a full-length ventilated rib and ends in a recessed target crown. Hogue overmolded grips interchange with every Python grip Colt sells, so the grips that govern felt recoil come off the Python shelf too. Safety is mechanical and internal, a transfer bar with a rebounding hammer and a cylinder latch safety, and Colt fits no manual lever to its revolvers. The top strap has no optic cut, though Colt does sell a plate that fits an RMSc-pattern dot to Pythons and Anacondas.

If you're cross-shopping, the Smith & Wesson Model 629 covers the same job for an MSRP of $1,139 with a 4.13-inch barrel and 9.63 inches of length, which is easier to wear on a belt. The Ruger Super Redhawk has an MSRP of $1,549, weighs 53.0 oz behind a 7.5-inch barrel and has scope mounts machined into its rib, so it arrives ready for glass. The Anaconda brings the Python action and the Python parts shelf behind it.